Publications
T. B. Haddou, D. Malfacini, G. Calo, M. D. Aceto, L. S. Harris, J. R. Traynor, A. Coop, H. Schmidhammer, M. Spetea. Exploring pharmacological activities and signaling of morphinans substituted in position 6 as potent agonists interacting with the μ opioid receptor. Molecular Pain 2014, 10, 48.
M. D. Metcalf, A. D. Rosicky, H. E. Hassan, N. D. Eddington, A. Coop, C. W. Cunningham, S. L. Mercer. Opioids and efflux transporters. Part 4: Influence of N-substitution on P-glycoprotein substrate activity of noroxymorphone analogues. Bioorg. Med. Chem. Lett., 2014, 24, 3592-3595.
J. R. Healy, P. Bezawada, J. Shim, J. W. Jones, M. A. Kane, A. D. MacKerell, Jr, A. Coop, R. R. Matsumoto. Synthesis, Modeling, and Pharmacological Evaluation of UMB 425, a Mixed μ Agonist/δ Antagonist Opioid Analgesic with Reduced Tolerance Liabilities. ACS Chemical Neuroscience 2013, 4, 1256-1266.
Also see: http://www.baltimoresun.com/health/bs-hs-new-opioid-20160624-story.html
and http://www.theatlantic.com/magazine/archive/2016/06/the-future-of-getting-high/480735/
