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Man-Kyo Chung, DMD, PhD

Professor, Department of Pain and Neural Sciences

SCHOOL OF DENTISTRY

  • Research interests

    Ion chanels in nociceptors


     

    Transient receptor potential channels


     

    Molecular mechanisms of tooth pain


     

    Peripheral mechanisms of craniofacial muscle pain

  • Research approaches

    Electrophysiology


    cellular physiology


    molecular biology


    biochemistry


    mouse genetics

     

    ORCID ID:  mchung

Publications

  1. Chung M.K., Lee J., Joseph J., Saloman J.L., Ro J.Y. : Peripheral Group I metabotropic glutamate receptor activation leads to muscle mechanical hyperalgesia through TRPV1 phosphorylation in the rat. J Pain, 16:67-76, 2015.
  2. Joseph J., Wang S., Lee J. Ro J.Y., Chung M.K.* : Carboxy terminal domain of transient receptor potential vanilloid 1 contains distinct segments differentially involved in capsaicin- and heat-induced desensitization. J Biol Chem, 288:35690-35702, 2013.
  3. Wang S., Joseph J., Ro J.Y. Chung M.K. *: Modality-specific mechanisms of PKC-induced hypersensitivity of TRPV1: S800 is a polymodal sensitization site. Pain 1156:931-941, 2015.
  4. Wang S., Lee J., Ro J.Y., Chung M.K. : Warmth suppresses and desensitizes damage-sensing ion channel TRPA1, Mol Pain, 8:22, 2012.
  5. Chung M.K., Lee J., Duraes G., Ro J.Y.: Lipopolysaccharide-induced pulpitis up-regulates TRPV1 in trigeminal ganglia, J Dent Res, 90: 1103-1107, 2011.