Matthew Frieman, PhD
Titles
Alicia and Yaya Professor of Viral Pathogen Research
Center for Pathogen Research
Department of Microbiology and Immunology
School Affiliation
School of Medicine
Specialties
Virology
Coronaviruses
Therapeutics
About
Phone: 4107062539
Email: MFrieman@som.umaryland.edu
I am the Alicia and Yaya Professor of Viral Pathogen Research in The Department of Microbiology and Immunology in The University of Maryland School of Medicine. My laboratory focuses on the pathogenesis of Coronaviruses to better understand how they cause disease. For the past 17 years, I have studied the highly pathogenic SARS-CoV-1, MERS-CoV, and SARS-CoV-2 via genetic, molecular, virological, immunological, and cell biological techniques. We focus on identifying viral proteins that control replication and host protein pathways as well as assessing those viral proteins and host proteins in animal model systems. In addition, we have investigated other human respiratory viruses including seasonal coronaviruses, rhinovirus, influenza virus and respiratory syncytial virus. We have used the combination of in vitro (air-liquid-interface, Lung Chip, human immortalized lung cells) and in vivo models (mouse models of SARS-CoV, SARS-CoV-2, MERS-CoV, Influenza virus) to identify host factors that affect multiple viruses and for the development and evaluation of therapeutics for these important respiratory viruses.
For interview requests, please contact the Office of Communications and Public Affairs.
Tagged: The Future of Health Care Global Health Research and Innovation