Leslie Costello has been a member of the University of Maryland School of Dentistry faculty since 1980, distinguishing himself as an educator and biomedical researcher.
Dr. Costello, whose investigative focus is on the metabolism of cancer cells, has received more than five decades of extramural grant support and made significant contributions to the scientific understanding of cancer — particularly prostate cancer. He received his first National Institutes of Health (NIH) and National Science Foundation grants in 1962 and has been awarded approximately $30 million through 31 grants, including 23 from NIH.
His discoveries and insights have had widespread implications for the understanding and treatment of prostate cancer, as well as breast, pancreatic, liver, and head and neck cancers, opening important new avenues of investigation into diagnosis and patient care, including the potential use of zinc as a biomarker for prostate cancer.
A prolific author, Costello has produced more than 175 reviewed articles in high-impact journals such as the Archives of Biochemistry and Biophysics, Journal of Cancer Research and Clinical Oncology, and the Journal of Cellular Biochemistry, as well as co-edited, authored, or contributed chapters to five books. Since 1975, his scientific articles have been cited more than 6,000 times, according to Google Scholar. Additionally, he has served as a reviewer for scientific journals including the Journal of Cellular and Comparative Physiology, Science, The Prostate, and Endocrinology.
Elected to the Rho Chi Honor and the Sigma Xi societies, Costello is a member of many other professional associations including the American Physiology Society, Endocrine Society, Maryland Biological Society, and Society for Basic Urological Research. He has a bachelor’s degree in zoology, a master’s in zoology/biochemistry, and a PhD in physiology/biochemistry, all from the University of Maryland, College Park.